Which substance can cause death if not medically monitored when a person is in withdrawal?

Alcohol withdrawal can lead to severe complications that pose significant health risks, including the potential for death if not medically monitored. This occurs because alcohol dependence alters the brain's chemistry, and when alcohol is abruptly discontinued, it can result in a condition known as Delirium Tremens (DTs). DTs can manifest with symptoms such as severe agitation, hallucinations, seizures, and autonomic instability, which can be life-threatening.

Medical supervision during withdrawal is critical in managing these risks effectively, typically through a monitored detoxification process and the use of medications to alleviate withdrawal symptoms and prevent complications. While withdrawal from other substances, such as opioids or benzodiazepines, can also be dangerous and require medical attention, alcohol withdrawal is especially known for its potential lethality if not properly managed.